
Black Box AI?
Not in BioMedicine.
We help scientists reason across complex biology to uncover evidence-backed discoveries faster.

MateBio is building the biological reasoning infrastructure for the next generation of AI scientist systems.
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By combining SPOKE, a large-scale biomedical knowledge graph, with Whyspr, an agentic AI platform, MateBio enables researchers to explore complex biology, connect fragmented evidence, and generate transparent, testable hypotheses across the discovery pipeline.
Multi agent reasoning
Whyspr turns biomedical chaos into clear, testable insight. Powered by MateBio’s SPOKE knowledge graph, it lets AI agents reason across biology, patients, and real-world evidence. The result: faster discoveries, smarter decisions, and science you can trust.
Explainable AI
SPOKE's connections are scientifically traceable. making it trustworthy for regulatory approval
Industry-Proven
Our solutions are backed by 10+ years of experience and a proven track record of success in pharma and biotech and are used by leading organizations like Pfizer, NASA, and Sanofi​.
Depth & Breath
Over 80 curated databases across genomics, proteomics, toxicology, EHRs, and more, compared to others that rely on noisy, unverified literature
Companies and Organizations that Trusted MateBio


























Working with the Best Partners
